Detailed Adsense Information
There is not much. Most people who claim to be AdSense experts parrot what is written on the dozen or so official AdSense pages.
Your ad layout should be different depending on many factors. Here are some examples of websites with the different layouts.
Much in the same way you sell a product, you want to be able to sell the ads. Thus it does not make sense to have the ads displayed in an offensively disruptive manner. The layout and design should blend. Google likes the tower ad, but ad layout should depends on different variables. If you throw your ads up in an offensive way you are killing off any long term loyalty you may have hoped to build.
Placing AdSense ads at the side of the content
Much the same way users have burned out on banner ads people may eventually get burned out on text ads.
Generally you will want the ads in the normal line of view by using a thin page format. This current site is not doing as good at selling ads as it could be. I have taken the ads off this page so I do not break any terms of service, but they were in that far right blue column (bad location)
If you do not want ads to interfere with your core business and are looking for a small supplement to your income you may want to use the wider page width and have the AdSense ads blend in at the edge of the page.
* If you have a "click happy" audience this may be the format for you
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